Neural Stem Cell Transplantation and Mechanisms for Functional Recovery
نویسندگان
چکیده
منابع مشابه
Neural Stem Cell Transplantation and Mechanisms for Functional Recovery
Neural stem cell transplantation has demonstrated its therapeutic potential in many neurological disorders. The long-thought prime mechanism of action was the replacement of cells lost to injury or neuro degeneration. Now, more and more evidence has provided insight into other bystander mechanisms through which these cell grafts could bring about a functional and structural restorative benefit....
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Thalassemia is an autosomal recessive disorder associated with defective synthesis of the α- or β-chain of hemoglobin. For β-thalassemia major patients, therapeutic options are either monthly red cell transfusions and chelation therapy or allogeneic stem cell transplant. Stem cell transplant is the only curative approach and success is inversely correlated with the degree of iron overload and h...
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Transplants of neural tissue have been used for nearly 100 years in order to clarify the mechanisms that underlie development and regeneration of the nervous system. With reports from Sweden and Mexico that autografts of adrenal medulla produce at least transient and perhaps dramatic improvement in patients severly disabled by Parkinson's disease, the techniques of neural transplantation have ...
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BACKGROUND AND PURPOSE Cell transplantation has been used to reduce behavioral deficit in cerebral ischemia. However, there is no report about cell transplantation in experimental intracerebral hemorrhage (ICH). We hypothesize that intravenously transplanted human neural stem cells (NSCs) can migrate and differentiate into neurons or glial cells, thereby improving functional outcome in ICH. M...
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Tissue and cell transplantation are regarded as a popular procedure in clinical sciences, prospecting a new horizon for several incurable diseases. Along with its usefulness, many ethical concerns accompany this development. The ethical issue of organ transplant is unique to the source used which includes: living related, living unrelated, cadaveric, and xenotransplant. Obtaining organs has a s...
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ژورنال
عنوان ژورنال: Journal of Stem Cell Research & Therapeutics
سال: 2016
ISSN: 2475-5540
DOI: 10.15406/jsrt.2016.01.00012